Maternal Lifestyle and Behavioral Factors Affect Risk of Spontaneous Preterm Birth

Vasculopathic and thrombophilic risk factors for spontaneous preterm birth.

BACKGROUND Mothers who give birth to preterm infants are at increased risk of mortality from coronary heart disease and stroke, but the biological pathways underlying these associations have not been explored. METHODS We carried out a case-control study nested in a large (n = 5337) prospective, multicentre cohort. All cohort women had an interview, examination and venipuncture at 24-26 weeks....

Maternal Periodontal Disease as a Potential Risk Factor for Preterm Birth and Low Birth Weight

Background and Aim: Periodontal disease may cause adverse pregnancy outcomes such as low birth weight (LBW) or preterm birth (PTB). In the present study, mothers with one of these two delivery complications were analyzed regarding presence/absence of periodontal disease as a possible risk factor in comparison with related medical risk factors.   Materials and Methods: In this cross-sectiona...

Maternal stress/distress, hormonal pathways and spontaneous preterm birth.

BACKGROUND Although second-trimester blood corticotrophin-releasing hormone (CRH) levels are robustly associated with preterm birth, the findings with respect to cortisol have been inconsistent, as have been those relating stress hormones to measured stressors and maternal distress. METHODS We measured plasma CRH, adrenocorticotrophic hormone (ACTH), cortisol, cortisol-binding globulin, oestr...

maternal risk factors and neonatal outcome of the admitted patients for preterm spontaneous uterine contractions

High maternal serum ferritin in early pregnancy and risk of spontaneous preterm birth.

Previous studies have reported inconsistent associations between maternal serum ferritin concentrations and the risk of spontaneous preterm birth (sPTB). The aim of the present study was to examine the association between Fe biomarkers, including serum ferritin concentrations, and the risk of total ( 75th percentile ( ≥ 43 μg/l) (OR 1.49, 95% CI 1.06, 2.10) and >90th percentile ( ≥ 68 μg/l) (OR...